Hi Micki-
Thanks for reaching out, and thanks for choosing the Total Upkeep WordPress backup plugin.
In theory, the settings you use for Total Upkeep’s FTP storage will be the same ones you’re using in CyberDuck, the FTP client for Mac.
One thing to keep in mind that if those CyberDuck settings are what you use to access your WordPress site, you don’t actually need to use FTP, your backups are already stored on your hosting account.
Double-check that the hostname, port, and protocol also match what you’re using in CyberDuck, and double-check the username and password. You may need to add an @domain.com to the end of your username as well, depending on your FTP setup.
Your hosting provider might also be able to provide more details if they can check the FTP Messages log to see if they can spot the error. Provide them with your IP address and the approximate time you tried to connect and got the error, and they should be able to locate the errors in their logs.